Repetitive stress injury (RSI) is one among fast developing occupational disease among population due to altered lifestyle, irregular body postures during work / physical activities etc. which is characterized by injuries to that particular site, associated with severe pain, tired feeling, stiffness, tingling etc. As per studies, 57% of working age adults reporting with Shoulder pain. Āyurvēda saṁhitā granthās explain such conditions in different orientation. Based on the guidelines mentioned in saṁhitās for understanding Anukta vyādhi, one can understand the RSI too. Trividha bodhya sangraha is one of unique orientation which is embedded in Nidanapancaka itself. Nidāna pañcaka is one among the mandatory criteria for any vyādhi. Here also same methodology followed to understand RSI in terms of Āyurvēda. It is proposed that RSI is to be understood as Vāta pradhāna Tridōṣa duṣṭi condition which mainly follows Samanya Vātavyādhi nidāna & Lakṣaṇas. In specific RSI can be appreciated in gata vāta Lakṣaṇas. Based on the involvement of nidāna, dōṣa, dushya, lakṣaṇa etc diagnosis of RSI can be made in Initial stages as Mamsa & Medhogata vāta. In Later stages as Asthi & Majjagata vāta.