Introduction: Stress has been those primitive diseases that man has been suffering with. Though stress seems relatively new disease, but traces of stress information has been found in classical text of Ayurveda. Charka and Sushrutha samhithas has elaborated the information about stress in different contexts.

Materials and methods: A systematic review was done in texts of Ayurveda and contemporary books, and National and International Journals were done. Key words like Sahasa, Stress, Occupational stress, Occupational Health were reviewed.

Results and Discussion: The role of stress in the aetiology of several diseases is well recognized in Ayurvedic science. The stress can be understood with the term sahasa in Ayurveda. Sahasa by causing ojahksaya (loss of immunity) increases the susceptibility of the body to various diseases. Caraka advises to avoid sahasa as it adversely affects the body, Different types of stressors physical, psychological and environmental as they vitiate doshas are implicated in the aetiology of several diseases.

Conclusion: Occupational stress can be understood under the concepts of Pragnaparadha, Sahasa, Manasikaroga. The treatment approach being stress avoidance is the ideal.