Introduction: Diarrhoea is a major cause of morbidity and mortality amongst under five children particularly in Nigeria. Proper home based management of children is critical in the survival of children with diarrhoea.

Methodology: This was a cross-sectional hospital based study conducted amongst mothers of children receiving immunization in a secondary health facility in Benin City. It involved the administration of pre-tested questionnaires to the mothers.

Data obtained were arranged into tables and analysed using the statistical package for social sciences (SPSS Version 20). Chi-square was used to determine the relationship between qualitative variables. P values< 0.05 was set as the level of significance.

Results: A total of 200 mothers were recruited for the study. 156(76.1%) of the respondents had good home care practices in the management of diarrhoea. 75(48.1%) of the respondents who had good knowledge of diarrhoea had good home care practices. Respondents with tertiary and secondary levels of education were found to be more likely to have good home care practices (odds ratio of 1.030 and 2.184 respectively).

Conclusion: This study showed that there was a high percentage of respondents with good home care practices in the management of diarrhoea.