The survival of the poultry industry is currently threatened in the majority of developing nations, particularly in Nigeria, by the shortage and high cost of conventional poultry feed ingredients. The poultry sector is essential for producing high-quality animal protein quickly enough for the world's expanding population. The main objective of this study is to determine the effect of non-conventional protein seed cakes that will be used in the replacement of full fat soybeans on broiler chicken production. A total number of 300 day old broiler (Cobb-500) chickens were purchased from Olam farm, Chukun hatchery. The chicks were randomly allotted to five dietary treatments with four (4) replicates. The birds were kept under deep litter management system and timber shaving was used as litter materials to cover the floor. The study comprised of four iso-nitrogenous and iso-caloric dietary treatments in both the starter (23% CP, 2800kcal/kg ME) and finisher rations (20% CP, 3000kcal/kg ME). The rations-based diets were Full fat Soybean meal, Soybean cake, Groundnut cake, Sesame seed meal and Palm kernel cake designated as diet T1, T2, T3, T4 and T5 respectively for both the starter and finisher diets. The results for the performance of broilers fed with Protein seed cake sources at the starter, finisher and overall phases revealed a very high significant difference (P < 0.001) in all the parameters, daily feed intake (DFI), daily weight gain (DWG), and feed conversion ratio (FCR), where diets T2, T1, T3 and T4 were the highest, while diet T5 was the least, however, the mortality rate was not significantly different (P>0.05) among the treatment means. The results of carcass characteristics revealed that there were very high significant differences (P<0.001) among the treatment means for live weight., Plucked Weight, Eviscerated, Carcass, Neck, Leg, Drumstick, Breast weights. A high significant difference (P<0.01) was obtained in Thigh and Head weights, while a significant difference (P<0.05) was found in dressing percentage where diet T2 is the highest in all the parameters while the least was in diet T5. Based on the results obtained in this study, it can be concluded that, with the exception of Palm kernel seed cake, all the other non-conventional protein seed cakes (Soybean cake, Groundnut cake, and Sesame seed cake) can effectively replace full fat soybean meal for effective growth performance, carcass and gut characteristics of broiler chickens.