In seafood, bivalve is one of the richest sources of balanced food but has a high level of heavy metal concentration in the aquatic environment and ultimately causing a negative effect on public health. Heavy metals are the common inorganic pollutant in the environment and their occurrence is a characteristic threat to human health due to their toxic effect on the biotic system. Most biological and geochemical factors affect the uptake and bioaccumulation in marine organisms. Marine organisms reflect the rising level of environmental contamination by industrial wastage and domestic discharges from urbanized areas. The objective of this work was to gather information on the presence of environmental contamination in different aquatic organisms and mollusks. A lack of researchers focused on nutritional composition, bioaccumulation, and mollusks as bioindicators for heavy metal pollution in aquatic organisms.