The main purpose of the study was to examine the relationship between intra-domestic chores on girls’ retention in secondary schools of Qardho District, Karkaar Region of Somalia; this study used, mixed methods of both qualitative and quantitative approaches. The findings revealed the secondary school girls are assigned too many intra-domestic and chores which affect their retention in secondary schools. The results indicate that intra-domestic chores accounts for about 73.9% of the variation in girls’ retention in secondary schools of Qardho District of Karkaar Region of Somalia. This implies that minimal intra-domestic chores significantly account for high girls’ retention in secondary schools of Qardho District of Karkaar Region of Somalia. This therefore, requires that Qardho District to ensure that intra-domestic chores are minimal for girls since they play a significant role towards their retention in secondary schools. The coefficients indicate that a unit increase in intra-domestic chores would reduce or decrease girls’ retention in secondary schools by a factor of 14.457. It was recommended that the local government authorities should collaborate with local communities to mobilize resource for constructing dormitories or hostels for girls to reduce the problems of girls spending more time and energy on doing household activities.