AIGC, as the latest Internet content production mode, further reshapes the labor practice of digital publishing industry with the iteration of intelligent technology, and brings brand-new opportunities and challenges for the transformation and upgrading of the publishing industry. The publishing labor mediated by generative AI represented by ChatGPT presents new features of automation and efficiency, humanization and interactivity, personalization and expansion, and promotes the changes of digital publishing labor practices in labor roles, labor forms, and labor processes. At the same time, the contradiction between the construction of labor subjectivity and the fall of labor rights, the optimization of labor functions and the degradation of labor capacity are all unavoidable real problems, and it is proposed to grasp the path of "human-machine" fusion publishing from the three dimensions of the government, technology, and laborers, so as to push forward the sustained and prosperous development of intelligent publishing.