This study investigated the effects of different soil amendments, including Palm Oil Mill Effluents (POME), cow dung, and NPK fertilizer, on soil chemical properties in two locations: Ekiti State University Teaching and Research Farm (EKSU) and Onu-Ijelu High School Agricultural Farm. The soil properties before the application of treatments were analyzed, and both locations were found to have loamy sand soil texture with slightly acidic to strongly acidic pH levels. The organic matter and nitrogen content were low in both soils, while phosphorus content was considered average. The exchangeable cations varied between low and moderate levels for the two sites. The initial soil properties served as a baseline for evaluating the impact of the amendments on soil fertility and crop productivity. Results indicated that NPK application led to a lower pH, consistent with its acidifying nature, while cow dung application resulted in the highest pH due to its capacity to buffer acidity. Both POME and cow dung increased the organic matter content of the soils. Additionally, the nutrient content of the amendments was generally high, especially in cow dung. The study emphasized the significance of these initial soil properties as a basis for evaluating the effectiveness of the amendments in improving soil fertility and crop productivity in the respective environments. Overall, the findings of this study contribute to understanding the impact of various soil amendments on soil chemical properties and crop growth, which is essential for sustainable agriculture.