Canna indica, commonly known as Indian shot, is a versatile plant with a history of traditional medicinal use. While it has been employed for various therapeutic purposes, its diuretic potential remains relatively unexplored. This study investigates the diuretic activity of the hydroalcoholic extract derived from Canna indica rhizomes. Hydroalcoholic extract of Canna indica rhizomes was prepared and subjected to a comprehensive phytochemical analysis to identify the presence of active compounds. Acute oral toxicity tests were conducted to assess safety. Diuretic activity was evaluated using Wistar rats as experimental models. Various diuretic parameters, including urine volume, electrolyte excretion, and creatinine clearance, were monitored. Furosemide was used as a positive control. Phytochemical analysis revealed the presence of flavonoids, alkaloids, and tannins in the hydroalcoholic extract. The extract was found to be safe at the tested doses. In the diuretic activity assessment, the extract exhibited a significant increase in urine volume, comparable to the effect produced by furosemide. Furthermore, the extract also demonstrated a noteworthy increase in electrolyte excretion and creatinine clearance, indicative of its diuretic potential. The hydroalcoholic extract of Canna indica rhizomes possesses diuretic activity, as evidenced by its ability to increase urine volume and enhance electrolyte excretion and creatinine clearance. These findings suggest that Canna indica may hold promise as a natural diuretic agent, deserving further investigation for its potential therapeutic applications.