Abstract

The functions of endothelial cells include physical barriers, sensory organs and endocrine organs, and all three of its functional abnormalities will lead to endothelial cell dysfunction, which will lead to the formation of atherosclerotic lesion initiation and continue to play an important role in the atherosclerotic process. Based on domestic and international research on endothelial cells and atherosclerosis, various causes of endothelial cell dysfunction and their important roles in the process of atherosclerosis will be explored, analyzed and synthesized, and finally the relationship between endothelial cell damage and the formation of atherosclerosis will be comprehensively analyzed at the molecular and individual levels, in order to provide new ideas and methods for the prevention and treatment of atherosclerosis.