The study investigated the effect of Emotional Intelligence (EI) on the Commitment level of Nurses at Tamale Central Hospital in Ghana. The study involved all the 253 Nurses working at the Tamale Central Hospital. A total of 253 questionnaires were returned, but after screening for suitability, 248 responses were used for the study. Data was analysed using descriptive statistics and simple linear regression. Nurses' perception of emotions had a positive and significant relationship with Affective Commitment (B=0.153, p=0.028). Understanding emotions showed a stronger positive and significant relationship with Affective Commitment (B=0.358, p=0.001). Nurses' ability to regulate emotions also had a positive significant relationship with Affective Commitment (B=0.195, p=0.009). Nurses' perception of emotions positively significantly influenced Normative Commitment (B=0.175, p=0.011), indicating a sense of obligation towards the Organisation. Understanding emotions had a strong positive significant relationship with Normative Commitment (B=0.438, p=0.000). Nurses' perception of emotions showed a positive significant relationship with Continuance Commitment (B=0.315, p=0.000), which is commitment based on the costs associated with leaving the Organisation. Emotional use and facilitation of thinking had a strong positive significant relationship with Continuance Commitment (B=0.484, p=0.000). The study recommends for Nurses and healthcare facilities managers to prioritise Emotional Intelligence issues among their Nursing staff. This will enable them to create a supportive and emotionally intelligent work environment, which may lead to increased commitment, improved job satisfaction, and better overall healthcare services.