Formulation and evaluation of finasteride microspheres
Abstract
The main aim of any drug therapy is to achieve a desire concentration of the drug in blood or tissue, which is therapeutically effective and non-toxic for an extended period of time. This can be achieved by proper design of sustained release dosage regimen. Various approaches have been developed for sustained release; Microspheres are the potential candidate for oral sustained release of drug. Finasteride microspheres were prepared by ionotropic gelation technique and different evaluation parameters were assessed, with a view to obtain oral control release of Finasteride. Optimized formulation shows that more sustained release was observed with the increase in percentage of sodium alginate. The best formulation was observed as F-2, by the observation of all results of the four formulations Finasteride microspheres.
How to Cite This Article
Syed Hafeez Ahmed, Shanthi Sagar, Uzma Begum, Ahba Umme Hani, Faiza Unnisa Taniya, Mohd Intesam Uddin, Mohammed Farhan Khan (2024). Formulation and evaluation of finasteride microspheres . International Journal of Multidisciplinary Research and Growth Evaluation (IJMRGE), 5(1), 156-160.