Background: Quality of life is becoming a central issue in patient care. In response to the increasing prevalence of hypertension worldwide, it is important to understand quality of life in hypertensive patients.

Objective: To describe the quality of life in hypertensive patients at Hue University of Medicine and Pharmacy Hospital.

Materials and Methods: The study was conducted on 172 subjects from May 2020 to July 2021 on hypertensive patients being treated at the Internal Medicine Department - Hue University of Medicine and Pharmacy Hospital. The study used a cross-sectional descriptive research method. Descriptive statistics were used to test the mean score of quality of life.

Results: WHOQOL – BREF Cronbach’s alpha coefficient for 26 items is 0.811, demonstrating good internal consistency. Based on the 33rd and 66th percentile scores on the total quality of life score, most of the patients participating in the study rated the quality of life at an average level when comprehensively surveyed across four domains. In which, the average score in the field of environment has the highest rate (mean score is 55.32; SD = 10.29), the lowest is in the field of physical health (average score 45.67; SD = 13.57).

Conclusion: WHOQOL - BREF is a useful and highly reliable tool to assess the quality of life of hypertensive patients. With these results achieved, action is needed to improve the quality of life of hypertensive patients.