Abstract

Malaria remains a critical public health issue in Africa, significantly contributing to morbidity and mortality rates. The availability, quality, and distribution of antimalarial medications are pivotal for effective malaria control, and these aspects are heavily influenced by regulatory frameworks. This literature review investigates the impact of regulations on malaria medication supplies in African countries, analyzing studies from the past decade. The review identifies key regulatory challenges, such as the prevalence of counterfeit and substandard drugs, inefficiencies in supply chain management, and the complexity of policy implementation. Additionally, the review highlights successful regulatory interventions, including quality assurance measures, pharmacovigilance systems, and regional harmonization efforts. Through a comprehensive examination of existing literature, the review underscores the critical role of regulatory bodies in ensuring the accessibility and efficacy of antimalarial medications. It also provides recommendations for enhancing regulatory frameworks, focusing on capacity building, infrastructure improvement, transparency, and international collaboration. By addressing these regulatory challenges, African countries can significantly improve the management and control of malaria, ensuring that effective treatments reach those in need.