Climatic-responsive architecture is characterized by its effective integration of local climate elements to achieve occupant thermal and visual comfort with minimal or no reliance on non-renewable energy sources. The study adopted architectural qualitative techniques to identify various climate-responsive façade in mixed-used high-rise developments in Lagos, Nigeria. Four forms of Double-Skin Façades, building integrated photovoltaics (BIPV), vertical greenery systems, and Advanced Shading Systems (Passive and Active) as essential strategies that should be incorporated into mixed-use-high-rise buildings. As a result, while lowering the building's need for artificial energy, the responsive façade produces a cozy interior. This means that when designing a building that adapts to the climate, the local climate in the area where the mixed-use high-rise structure is being taken into consideration. The study concluded that, given the growing popularity of mixed-rise construction in Lagos, Nigeria, the identified climate-responsive building techniques ought to be adopted.