Abstract

Bactria have important properties included an ability to adaption of environment by produce antimicrobial peptides, it have bioactivity against for many types of pathogenic bacteria and this character consider the best mechanisms that allow bacteria to defense from delete agent, as while as to compete of nutrient and habitat and space on environment, so these antimicrobial peptides production it call becteriocins. Bacteriocins was producing by many types of bacteria, it producing from Gram + / - bacteria and Arechae and generated by ribosome, classified od bacteriocin deepened of several methods, such as producing bacteria strains, size, structure and functional, mode of actions occurring by pore forming or proteins inhibition synthesis. in last years, there are important attention of bacteriocins application by using it on several field included Food industry as a bio preservative substance using it without needing to addition any of chemical or physical treatments, in addition it using on medical human health care as alternative pathway for treatment many multidrug resistant bacteria and on agriculture for plant growth promotion, these due to properties of bacteriocins as low toxicity, it have strong activity of target pathogenic with low concentration and easily obtain from environment.