Ensuring compliance and safety in global procurement operations within the energy industry is critical due to the sector's complex supply chains, high regulatory scrutiny, and inherent safety risks. This review explores key strategies and best practices that energy companies employ to maintain compliance and safety across global procurement processes. One critical area is the implementation of comprehensive procurement policies that align with local and international regulations, such as the International Organization for Standardization (ISO) standards and the Foreign Corrupt Practices Act (FCPA). Adopting robust supplier evaluation frameworks is essential to mitigate risks, ensuring that suppliers adhere to safety, environmental, and ethical standards. This includes rigorous vetting, ongoing audits, and the use of data analytics to monitor supplier performance. In addition, the incorporation of safety management systems (SMS) within procurement processes enhances the identification and mitigation of operational risks. Emphasizing Health, Safety, and Environmental (HSE) compliance, these systems enable companies to enforce strict safety protocols and maintain operational integrity. Another essential aspect is the integration of digital tools such as blockchain and artificial intelligence (AI) to ensure transparency and traceability throughout the supply chain, thereby reducing fraud, corruption, and regulatory breaches. Moreover, fostering collaboration between procurement, legal, and compliance teams helps in ensuring that contract management aligns with industry standards and safety regulations. The training and upskilling of procurement professionals on evolving regulations and safety protocols is also emphasized to maintain a proactive approach to compliance. Finally, addressing geopolitical risks, fluctuating market conditions, and regulatory changes is crucial to sustaining global procurement operations. This review highlights the need for a holistic approach that combines regulatory compliance, technological innovation, and a strong safety culture to ensure that procurement operations in the energy industry are efficient, compliant, and safe.