Abstract

The ongoing evolution of the COVID-19 pandemic has led to an increasing amount of study on Long COVID-19, defined by persistent symptoms that may remain for weeks or months following initial infection. Fibromyalgia (FM), a chronic disorder marked by pervasive pain, fatigue, and cognitive impairments, has become a notable issue among these symptoms. A literature study examining long COVID patients reveals that its predominant symptoms, such as fatigue, generalized pain, cognitive impairments, sleep problems, and mood disorders, closely resemble those associated with FM. A substantial percentage of long COVID patients fulfil the criteria for chronic overlapping pain conditions (COPCs), and the clinical progression of these illnesses is analogous. The potential mechanisms linking Long COVID-19 and FM are multifaceted, involving a combination of pathophysiological processes are discussed in this review paper.