This study is to measure the productivity of transport logistics included road, rail, marine, inlannd water and air transportation, the case of hochiminh City, Vietnam (HCM). The objective is to evaluate the labor productivity and capital productivity then assess how they impact on Gross Domestic Product (GDP) of HCM transport logistics. By applying Cobb – Douglas production function (Cobb-Douglas) and Multivariate regression (MR). The main findings are an increase 1% both Labor and Capital is accompanied by a more than 1% increase in products and the whole transport logistics system operates with increasing profits. The goods labor productivity and the passenger capital productivity impact on GDP of HCM transport logistics. The passengers labor productivity and the goods capital productivity do not impact on GDP of HCM transport logistics.