Education in the Society 5.0 Era requires the utilization of advanced information technology that enables the quick and effortless distribution of diverse knowledge in educational activities, unbound by time and space limitations. Technology integration in education is a crucial factor for the efficacy of the learning process. This study aims to create a flipped guided inquiry learning system utilizing the Discord application for buffer solution content and to assess its validity and practicality. The goal of this study is to provide a different approach to chemistry teaching that matches the requirements of the Merdeka Curriculum and the Society 5.0 period, particularly with regard to the content of buffer solutions. This study was carried out over six months, employing the Plomp and Educational Design Research (EDR) Models. The research involved conducting preliminary studies and prototyping phases. The participants in this study comprised lecturers and teachers as experts, together with nine students. Construct validity and content validity data were examined using Aiken's V formula and practicality percentage, respectively. The study's results indicated that the value of 0.89 for content and construct validity fell inside a valid category. Practical outcomes, with a score of 92%, are categorized as a practical category. Consequently, it can be confirmed that the developed learning system is both valid and practical, allowing for its efficiency to be evaluated in subsequent studies.