This paper presents a conceptual model for cultural responsiveness in peer-led learning and mentorship, aiming to address the growing need for inclusive educational practices in diverse learning environments. The model integrates key theories of cultural competence, peer mentoring, and collaborative learning, focusing on the adaptation of mentorship strategies to foster cultural awareness and inclusivity. Through a comprehensive literature review, the study highlights the gaps in current peer-led mentorship programs, which often overlook the cultural dynamics of mentor-mentee interactions. The model developed in this paper provides a structured framework for mentors to engage with students from diverse cultural backgrounds, promoting effective communication, mutual respect, and collaborative learning. The research methodology includes the development of the conceptual framework, data collection through surveys and interviews, and validation through pilot studies. The anticipated outcomes include enhanced inclusivity, improved learning outcomes, and the development of intercultural competencies. Implications for practice suggest that the model can transform peer-led learning programs by incorporating cultural responsiveness, thus contributing to a more equitable and supportive educational experience. Future research directions include exploring the model’s application in different cultural contexts and its impact on long-term academic and personal development.