The increasing strategic importance of multinational pipeline operations, especially in fragile environments, necessitates a paradigm shift toward intelligence-led security protocols. These infrastructures are critical to the global energy supply chain but are frequently targeted by non-state actors, insurgents, organized criminals, and opportunistic saboteurs in regions characterized by weak governance, socio-political instability, and limited law enforcement capacity. Traditional reactive security models are often insufficient to address the complex, dynamic, and cross-jurisdictional threats facing pipeline operations in such volatile settings. This conceptual and review-based paper proposes an intelligence-led framework tailored to multinational pipeline security, emphasizing proactive, data-driven approaches that integrate threat intelligence into risk mitigation and operational planning. Drawing on lessons from critical infrastructure sectors such as aviation, maritime transport, and national grid systems, the study explores how threat intelligence encompassing human intelligence (HUMINT), signals intelligence (SIGINT), and geospatial intelligence (GEOINT) can inform comprehensive security protocols. It further examines the role of emerging technologies, including drones, AI-powered analytics, and remote surveillance, in enhancing situational awareness and early warning capabilities. Key components of the proposed model include threat mapping, intelligence fusion, scenario simulations, and real-time decision-making mechanisms. This also highlights the importance of stakeholder coordination, public-private partnerships, and local community engagement to enable context-aware intelligence collection and foster trust. Attention is given to ethical and legal challenges such as data privacy, sovereignty, and compliance with international norms. Ultimately, this advocates for the institutionalization of intelligence-led security as a cornerstone of multinational pipeline governance in fragile environments. By doing so, organizations can improve operational resilience, minimize financial and reputational risks, and contribute to broader regional stability. The findings underscore the urgent need for adaptive, anticipatory security practices that transcend traditional boundaries and prepare critical infrastructure operators for evolving global security landscapes.