Islamic boarding schools have great potential as Islamic educational institutions that play a role in the economic empowerment of the people. In the context of improving community welfare and developing an Islamic value-based economy, pesantren can integrate Islamic values with entrepreneurial practices. This study aims to examine how pesantren entrepreneurship can be a solution in community economic empowerment and formulate the strategic role of pesantren in developing an Islamic values-based economy. This research uses a descriptive qualitative approach with a literature study method. Data were collected through literature review from various sources, including books, journals, and related documents that discuss pesantren entrepreneurship, Islamic economics, and Islamic value-based community empowerment. The analysis was conducted by examining the content and interpreting the role of pesantren in an integrative economic context. The results showed that pesantren that successfully develop entrepreneurship generally have a clear economic vision, progressive leadership, and integration of Islamic values in every aspect of their business. Pesantren entrepreneurship is proven to be able to increase economic independence, create jobs, and strengthen the social resilience of the surrounding community. The conclusion of this study is that pesantren have great potential as agents of economic change based on Islamic values, but still need policy support, managerial training, and strategic partnerships to expand their impact. Thus, the development of entrepreneurship in the pesantren environment is a concrete step in realizing the sustainable economic empowerment of the people based on sharia values.