With the continuous development of society, studying the relationship between urban-rural integration and industrial development has become an important part of promoting social progress. In order to better study the mutual influence between urban-rural integration and industrial development, this study constructs a coordinated coupling mechanism model of urban-rural integration and industrial development and conducts an overall analysis of the coupling status of urban-rural integration and industrial development in the Yangtze River Delta region. The study found that through methods and policies such as spatial carrier integration and digital chain integration in the Yangtze River Delta region at present, the coordination and coupling between the two are relatively good. However, the negative impact of the two still cannot be ignored.