Abstract

The study aimed to test the inhibitory activity of the alcoholic extract of turmeric, extract the active compound curcumin then diagnose it by using high performance liquid chromatography (HPLC), and compare its inhibitory activity with the alcoholic extract of turmeric against some types of fungi Fusarium spp. Where it was found that the alcoholic extract of the turmeric plant Curcuma longa had a slight significant effect against the tested isolates grown on the culture media Potato Dextrose Agar PDA, as measured by the inhibition percentage of isolates treated with curcumin extract at a probability level of 1%. The percentage of isolates of Fusarium tricinctum treated with alcoholic extract of turmeric was 54.73%. While the inhibition rate of the same isolate treated with curcumin extract was 75.66% at a concentration of 6 mg/ml, and the percentage of inhibition in the growth rate of fungi colonies treated with alcoholic extract of turmeric was 34.03%, Fusarium solani. While the inhibition rate in the average colony diameters of the same isolate treated with curcumin extract was 84.40%. Also, some active compounds were detected in the alcoholic extract of turmeric, each of which contained phenols and flavonoids, and their content of phenols was 689.5 mg/g for turmeric, while the percentage of flavonoids was 489.8 mg/g for turmeric. In testing the effect of copper oxide nanoparticles CuO NPs against the colony growth of Fusarium isolates, it was noted that there were no restrictions in the radial growth of colonies at all the concentrations used, but there was a decrease in the fungal density of F.tricinctum isolate colonies, and the color change of Fusarium solani colonies was also observed.