This study employed a descriptive qualitative research design to explore and understand the lived experiences of college students regarding digital fatigue in online and hybrid learning environments. A total of twenty (20) college student participants from Cebu City, Philippines were selected using criterion-based purposive sampling. Data were collected through a researcher-made open-ended questionnaire and semi-structed interviews conducted online. The gathered data were transcribed and analyzed using thematic analysis following Braun and Clarke’s framework. Findings revealed that students commonly experience physical, mental, and emotional symptoms such as eye strain, headaches, mental exhaustion, decreased motivation, and difficulty concentrating. Six (6) emergent themes were identified on students’ academic performance, engagement, well-being, and daily functioning. The study also revealed various coping strategies employed by students, though with varying levels of effectiveness. It is concluded that digital fatigue significantly affects students’ learning experiences and overall well-being in online and hybrid settings. It is recommended that educators and institutions implement balanced instructional strategies, manageable workloads, and supportive learning environments to reduce digital fatigue and promote student well-being.