The study was carried out to ascertain the information needs of ante-natal and post-natal mothers in Ignatius Ajuru University of Education Health Centre, Port Harcourt, Rivers State. The objective of the study was to ascertain the information needs of ante-natal and post-natal mothers in Ignatius Ajuru University of Education Health Centre. Survey research design was used to carry out the study while an instrument titled “Information Needs of Antenatal and Post-Natal Mothers (INAPNM) in Ignatius Ajuru University of Education Health Centre, Port Harcourt, Rivers State” was used for data collection. Five (5) research questions was designed for the two groups. Demographic findings revealed that women who use the health centre have attained tertiary height in their education. These women have peculiar needs, while common and similar information need is centred on breastfeeding. In the health centre, information by ante-natal mothers is received mainly during post-natal sessions. Major constraints faced by the women in accessing information is the frequent power failure.