Synthesis of 1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro phenyl)-1-oxo-2, 3-epoxy propane derivatives as Antimicrobial agents
Abstract
Epoxides are the natural phytoconstituents with several biological significance such as Anti-inflammatory, Antioxidant, Anticancer and Antimicrobial activity. The Series 1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro phenyl)-1-oxo-2, 3-epoxy propane derivatives was designed and synthesized from 1-(5-chloro-2-hydroxyphenyl)-3-(2-chlorophenyl)-prop-2-en-1-one.
Current research work screened for Iv-vitro anti-bacterial activity against Escherichia coli, Staphylococcus aureus (Pathogens obtained from animal), Xanthomonas citri and Xanthomonas malvacearum (Pathogens obtained from plant). The compound SAC-3 and SAC-6 shows good antibacterial activity while other shows moderate to good anti-microbial activity.
How to Cite This Article
Awinash S Chavan, Seema P Rathod (2023). Synthesis of 1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro phenyl)-1-oxo-2, 3-epoxy propane derivatives as Antimicrobial agents . International Journal of Multidisciplinary Research and Growth Evaluation (IJMRGE), 4(1), 01-05.