Sumbawa Island in West Nusa Tenggara Province holds significant potential for the development of sustainable maize agribusiness, particularly as a strategic commodity in the food and animal feed sectors. This review aims to formulate strategic management approaches for sustainable agribusiness by considering economic, environmental, and social dimensions. The study employs a literature review method, drawing on recent and relevant scholarly works. The analysis reveals that while maize significantly contributes to the local economy, its development faces numerous challenges, including land degradation, dependence on chemical inputs, limited market access, and inadequate technology adoption. Sustainable agribusiness strategies should encompass product diversification, the use of organic fertilizers, and the enhancement of farmers’ capacity through training, financial access, and multistakeholder collaboration. Such synergy between the government, farmers, and the private sector is essential. This paper underscores the need for a holistic approach that integrates economic, environmental, and social considerations to ensure the long-term sustainability of maize agribusiness on Sumbawa Island. The adoption of appropriate technologies, development of marketing networks, and improvement of production efficiency through environmentally friendly practices are strongly recommended to support farmer welfare while preserving ecological balance.